Categoria
Metilprednisolona [Inn-Spanish]
Nombres de marca,
Metilprednisolona [Inn-Spanish]
Analogos
Metilprednisolona [Inn-Spanish]
Marca los nombres de mezcla
Depo-Medrol with Lidocaine (Lidocaine Hydrochloride + Methylprednisolone Acetate) Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Sulfur) Methylprednisolone Sodium Succinate for Injection (Methylprednisolone + Water) Neo-Medrol (Methylprednisolone Acetate + Neomycin Sulfate) Neo-Medrol Acne Lotion (Aluminum Chlorohydrate + Methylprednisolone Acetate + Neomycin Sulfate + Sulfur)
Metilprednisolona [Inn-Spanish]
Formula quimica
C22H30O5
Metilprednisolona [Inn-Spanish]
RX enlace
http://www.rxlist.com/cgi/generic/methprd.htm
Metilprednisolona [Inn-Spanish]
FDA hoja
Metilprednisolona [Inn-Spanish]
MSDS (hoja de seguridad de materiales)
Metilprednisolona [Inn-Spanish]
Sintesis de referencia
Sebek, Spero, EE.UU. Pat. 2,897,218 (1959)
Metilprednisolona [Inn-Spanish]
Peso molecular
374.471 g/mol
Metilprednisolona [Inn-Spanish]
Punto de fusion
232.5 oC
Metilprednisolona [Inn-Spanish]
H2O Solubilidad
120 mg / L
Metilprednisolona [Inn-Spanish]
Estado
Solid
Metilprednisolona [Inn-Spanish]
LogP
2.134
Metilprednisolona [Inn-Spanish]
Formas de dosificacion
Tabletas, suspensión
Metilprednisolona [Inn-Spanish]
Indicacion
La terapia adyuvante para administración a corto plazo en la artritis reumatoide.
Metilprednisolona [Inn-Spanish]
Farmacologia
Metilprednisolona y sus derivados, succinato sódico de metilprednisolona y metilprednisolona, son glucocorticoides sintéticos utilizados como agentes antiinflamatorios o inmunosupresores.
Metilprednisolona [Inn-Spanish]
Absorcion
La biodisponibilidad oral del 80-99%
Metilprednisolona [Inn-Spanish]
Toxicidad
DL50 = 2000 mg / kg (por vía oral en ratas)
Metilprednisolona [Inn-Spanish]
Informacion de Pacientes
Persons who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or
measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.
Metilprednisolona [Inn-Spanish]
Organismos afectados
Humanos y otros mamíferos